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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 60830Generated: October 29, 2026

5-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acid → (5,5-Diethoxy-2-(hydroxymethyl)piperidin-1-yl)(5-(4-fluorophenyl)-2-methylthiazol-4-yl)methanone

https://huagongshe.com/reaction/60830

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acidHCID 22324125—
Reactant5,5-Diethoxy-2-piperidinemethanolHCID 89739172—
Product(5,5-Diethoxy-2-(hydroxymethyl)piperidin-1-yl)(5-(4-fluorophenyl)-2-methylthiazol-4-yl)methanoneHCID 89739753—

Reaction Steps

The title compound was prepared according to general procedure A using 5-(4-fluorophenyl)-2-methylthiazole-4-carboxylic acid and rac-(5,5-diethoxypiperidin-2-yl)methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-859d49219113445987c5fbc547119079
Source noteuspto-grants-2016_09