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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 60833Generated: October 29, 2026

5-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acid → tert-Butyl (1-(5-(4-fluorophenyl)-2-methylthiazole-4-carbonyl)-6-methylpiperidin-2-yl)methylcarbamate

https://huagongshe.com/reaction/60833

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acidHCID 22324125—
ReactantTert-butyl (6-methylpiperidin-2-yl)methylcarbamateHCID 62321238—
Producttert-Butyl (1-(5-(4-fluorophenyl)-2-methylthiazole-4-carbonyl)-6-methylpiperidin-2-yl)methylcarbamateHCID 89748251—

Reaction Steps

rac-tert-Butyl (1-(5-(4-fluorophenyl)-2-methylthiazole-4-carbonyl)-6-methylpiperidin-2-yl)methylcarbamate was prepared according to general procedure A using rac-tert-butyl (6-methylpiperidin-2-yl)methylcarbamate and 5-(4-fluorophenyl)-2-methylthiazole-4-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-1ebba1e104714efd819654560406491c
Source noteuspto-grants-2016_09