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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 60850Generated: October 30, 2026

2-Chlorobenzothiazole → rac-cis-(2-((Benzo[d]thiazol-2-ylamino)methyl)-3-methoxypiperidin-1-yl)(5-(4-fluorophenyl)-2-methylthiazol-4-yl)methanone

https://huagongshe.com/reaction/60850

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChlorobenzothiazoleHCID 11987—
Reactantrac-cis-(2-(Aminomethyl)-3-methoxypiperidin-1-yl)(5-(4-fluorophenyl)-2-methylthiazol-4-yl)methanoneHCID 131737138—
Productrac-cis-(2-((Benzo[d]thiazol-2-ylamino)methyl)-3-methoxypiperidin-1-yl)(5-(4-fluorophenyl)-2-methylthiazol-4-yl)methanoneHCID 131737140—

Reaction Steps

The title compound was prepared following the same general protocol as described for Example 12 using 2-chlorobenzothiazole and rac-cis-(2-(aminomethyl)-3-methoxypiperidin-1-yl)(5-(4-fluorophenyl)-2-methylthiazol-4-yl)methanone. MS (ESI) 497.0 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-0291c95e36564445811bcb9c18d27a20
Source noteuspto-grants-2016_09