HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 1-Benzyl-2-(((tert-Butoxycarbonyl)amino)methyl)-3-methylpyridin-1-ium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Tert-butyl ((3-methylpyridin-2-yl)methyl)carbamate | HCID 63789587 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1-Benzyl-2-(((tert-Butoxycarbonyl)amino)methyl)-3-methylpyridin-1-ium bromide | HCID 89739374 | — |
Reaction Steps
tert-Butyl ((3-methylpyridin-2-yl)methyl)carbamate (4.5 g) and benzyl bromide (2 eq) in 80 ml of acetonitrile was heated in a sealed tube at reflux overnight and then concentrated in vacuo to give the title compound and was used without further purification. MS (ESI) 313 (M+H)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09440982B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-31d2e056ce694d11a0ef771d77b1c6f9 |
| Source note | uspto-grants-2016_09 |