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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 60937Generated: October 26, 2026

5-Methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoic acid → 5-Methyl-2-(2-methyl-4-pyrimidinyl)benzoic acid

https://huagongshe.com/reaction/60937

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoic acidHCID 81111500—
ReactantMethyl 5-methyl-2-(2-methylpyrimidin-4-yl)benzoateHCID 117727652—
Product5-Methyl-2-(2-methyl-4-pyrimidinyl)benzoic acidHCID 117727825—

Reaction Steps

The title compound was synthesized following the same general protocol as described for 5-methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoic acid in Example A1, using methyl 5-methyl-2-(2-methylpyrimidin-4-yl)benzoate. ESI-MS (m/z): 229 [M+1]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-6e36181d1104415e89eeae68ac9ca791
Source noteuspto-grants-2016_09