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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 609603Generated: October 25, 2026

4-Aminomethyl-1-N-butylpiperidine → N-[(1-n butyl-4-piperidyl)methyl] 5-fluoroindole-3-carboxamide

https://huagongshe.com/reaction/609603

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Aminomethyl-1-N-butylpiperidineHCID 10442133—
Reactant5-Fluoroindole-3-carboxylic acid chlorideHCID 54328249—
ProductN-[(1-n butyl-4-piperidyl)methyl] 5-fluoroindole-3-carboxamideHCID 5378903064%

Reaction Steps

5-Fluoroindole-3-carboxylic acid chloride was reacted with (1-n butyl-4-piperidyl)methylamine (Description 1a) as in the method of Description 1b to afford N-[(1-n butyl-4-piperidyl)methyl] 5-fluoroindole-3-carboxamide as an off-white solid (64%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05998409
Source datasetuspto-grants-1999_12
ORD IDord-d0b509eb741e4c9ab71be7b32083aa20
Source noteuspto-grants-1999_12