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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 61007Generated: October 28, 2026

3-Fluoro-2-methoxybenzoic acid → ((2S,3R)-2-(Aminomethyl)-3-methylpiperidin-1-yl)(3-fluoro-2-methoxyphenyl)methanone

https://huagongshe.com/reaction/61007

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-2-methoxybenzoic acidHCID 2737361—
Reactant((2S,3R)-2-(Aminomethyl)-3-methylpiperidin-1-yl)(5-methyl-2-(1-methyl-1H-pyrazol-4-yl)phenyl)methanoneHCID 117728145—
Product((2S,3R)-2-(Aminomethyl)-3-methylpiperidin-1-yl)(3-fluoro-2-methoxyphenyl)methanoneHCID 117727693—

Reaction Steps

The title compound was prepared following the same general protocol as described for ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(5-methyl-2-(1-methyl-1H-pyrazol-4-yl)phenyl)methanone in Example A1 using 3-fluoro-2-methoxybenzoic acid. MS (ESI) 281 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-f3b857c1da634f24a69ef3561630252c
Source noteuspto-grants-2016_09