Phenylhydrazine → 1-(4-Chlorophenyl)-3-methyl-1H-pyrazole

HRID 610117Notes

Reaction equation

HRID 610117 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][NH2:9])=[CH:4][CH:3]=1.[C:10]1(NN)[CH:15]=CC=[CH:12][CH:11]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH:15]=[CH:10][C:11]([CH3:12])=[N:9]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 7516PhenylhydrazineHCID 70624(4-Chlorophenyl)hydrazine

Product 1

HCID 179399681-(4-Chlorophenyl)-3-methyl-1H-pyrazole

Procedure

This compound was prepared by the same methodology described for EXAMPLE 8 with 4-chlorophenyl hydrazine · HCl substituted for phenyl hydrazine and 2-amino-5-(2-N-t-butylaminosulfonylphenyl)pyridine was used in the coupling step. There was obtained the title compound; HRMS (M+H)+ : calc. 468.089714; found 468.088873.

Workup

  1. customThis compound was prepared by the same methodology

Sources & evidence

ORD record
ord-aceddcd41e9842d6bbb76c3ad1c2d59d
Source dataset
uspto-grants-1999_12
Patent number
US05998424

Reaction notes

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