2-Benzylamino-4-(t-butyl)amino-3,5,6-trifluoropyridine → 2-Amino-4-(t-butylamino)-3,5,6-trifluoropyridine

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Reaction Steps

To 13 ml of acetic acid were added 4.0 g of the crude 2-benzylamino-4-(t-butyl)amino-3,5,6-trifluoropyridine as described above together with 0.43 g of 10% palladium on carbon, and the mixture was hydrogenated at 60° C. for 6 hours. The catalyst was separated by filtration, and the solvent and the like were distilled off under reduced pressure to obtain the title compound as a brown crude oil.

Provenance & Evidence