Hydrochloric Acid → 1-(2-ethylmethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)-6-phenylhexan-1-one hydrochloride

HRID 611177Notes

Reaction equation

HRID 611177 reaction equation
[CH2:1]([C:3]1[O:24][C:6]2[CH2:7][N:8]([C:11](=[O:23])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH2:9][CH2:10][C:5]=2[C:4]=1[CH2:25][NH:26][CH3:27])[CH3:2].[ClH:28]>CO>[ClH:28].[CH2:1]([C:3]1[O:24][C:6]2[CH2:7][N:8]([C:11](=[O:23])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=3)[CH2:9][CH2:10][C:5]=2[C:4]=1[CH2:25][NH:26][CH3:27])[CH3:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 675849261-(2-ethylmethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)-6-phenylhexan-1-one

Product 1

HCID 675865321-(2-ethylmethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)-6-phenylhexan-1-one hydrochloride

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

1-(2-Ethylmethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)-6-phenylhexan-1-one 0.108 g was dissolved in 2 ml of methanol; hydrogen chloride in methanol was added in excess, followed by stirring. This mixture was concentrated to yield the desired product.

Workup

  1. concentrationThis mixture was concentrated

Sources & evidence

ORD record
ord-49c49c6045da4226a660094decfb573c
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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