Hydrochloric Acid → HCID 19600026, compound

HRID 611212Notes

Reaction equation

HRID 611212 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([S:14]([CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)(=[O:16])=[O:15])[CH2:8][C:7]=2[CH:6]=1)[CH3:3].[ClH:28]>CO>[ClH:28].[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([S:14]([CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]3[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=3)(=[O:16])=[O:15])[CH2:8][C:7]=2[CH:6]=1)[CH3:3]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19599983HCID 19599983, compound

Product 1

HCID 19600026HCID 19600026, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

N,N-Dimethyl-[5-(5-phenylpentylsulfonyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine 0.244 g was dissolved in 2 ml of methanol; hydrogen chloride in methanol was added in excess, followed by stirring. After this mixture was concentrated, diethyl ether was added; the resulting solid was filtered and washed with diethyl ether to yield the desired product.

Workup

  1. concentrationAfter this mixture was concentrated
  2. additiondiethyl ether was added
  3. filtrationthe resulting solid was filtered
  4. washwashed with diethyl ether

Sources & evidence

ORD record
ord-74ff4d90d44447cea414b9d38c3bec47
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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