Hydrochloric Acid → N,N-dimethyl-[6-(4-benzoylbenzoyl)-5,6,7,8-tetrahydro-4H-furo[2,3-d]azepin-2-ylmethyl]amine hydrochloride

HRID 611229Notes

Reaction equation

HRID 611229 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:30][C:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:29])[C:15]3[CH:20]=[CH:19][C:18]([C:21](=[O:28])[C:22]4[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=4)=[CH:17][CH:16]=3)[CH2:12][CH2:13][C:7]=2[CH:6]=1)[CH3:3].[ClH:31]>CO>[ClH:31].[CH3:3][N:2]([CH2:4][C:5]1[O:30][C:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:29])[C:15]3[CH:20]=[CH:19][C:18]([C:21](=[O:28])[C:22]4[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=4)=[CH:17][CH:16]=3)[CH2:12][CH2:13][C:7]=2[CH:6]=1)[CH3:1]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19599946N,N-dimethyl-[6-(4-benzoylbenzoyl)-5,6,7,8-tetrahydro-4H-furo[2,3-d]azepin-2-ylmethyl]amine

Product 1

HCID 19600246N,N-dimethyl-[6-(4-benzoylbenzoyl)-5,6,7,8-tetrahydro-4H-furo[2,3-d]azepin-2-ylmethyl]amine hydrochloride

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

N,N-Dimethyl-[6-(4-benzoylbenzoyl)-5,6,7,8-tetrahydro-4H-furo[2,3-d]azepin-2-ylmethyl]amine 0.156 g was dissolved in 2 ml of methanol; hydrogen chloride in methanol was added in excess, followed by stirring. This mixture was concentrated to yield the desired product.

Workup

  1. concentrationThis mixture was concentrated

Sources & evidence

ORD record
ord-1840e7b99c7942d5ab39ffe2736661e4
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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