Hydrochloric Acid → HCID 19599943, compound

HRID 611248Notes

Reaction equation

HRID 611248 reaction equation
C(O[C:6]([N:8]([CH2:10][C:11]1[O:35][C:14]2[CH2:15][N:16]([C:19](=[O:34])[C:20]3[CH:25]=[CH:24][C:23]([C:26](=[O:33])[C:27]4[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=4)=[CH:22][CH:21]=3)[CH2:17][CH2:18][C:13]=2[CH:12]=1)C)=O)(C)(C)C.[ClH:36]>CO>[ClH:36].[CH3:6][NH:8][CH2:10][C:11]1[O:35][C:14]2[CH2:15][N:16]([C:19](=[O:34])[C:20]3[CH:25]=[CH:24][C:23]([C:26](=[O:33])[C:27]4[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=4)=[CH:22][CH:21]=3)[CH2:17][CH2:18][C:13]=2[CH:12]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19600179HCID 19600179, compound

Product 1

HCID 19599943HCID 19599943, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

N-tert-Butoxycarbonyl-N-methyl-[6-(4-benzoylbenzoyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine 0.127 g (0.268 mmol) was dissolved in 5 ml of methanol; 1 ml of concentrated hydrochloric acid was added, followed by stirring for 30 minutes. This solution was concentrated to yield the desired product.

Workup

  1. concentrationThis solution was concentrated

Sources & evidence

ORD record
ord-747c03c9bf574118b881b8325baaa0b0
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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