Hydrochloric Acid → N,N-dimethyl-[6-[4-(2-thenoyl)benzoyl]-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine hydrochloride

HRID 611302Notes

Reaction equation

HRID 611302 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:28][C:8]2[CH2:9][N:10]([C:13](=[O:27])[C:14]3[CH:19]=[CH:18][C:17]([C:20](=[O:26])[C:21]4[S:25][CH:24]=[CH:23][CH:22]=4)=[CH:16][CH:15]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3].[ClH:29]>CO>[ClH:29].[CH3:3][N:2]([CH2:4][C:5]1[O:28][C:8]2[CH2:9][N:10]([C:13](=[O:27])[C:14]3[CH:19]=[CH:18][C:17]([C:20](=[O:26])[C:21]4[S:25][CH:24]=[CH:23][CH:22]=4)=[CH:16][CH:15]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:1]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19599886N,N-dimethyl-[6-[4-(2-thenoyl)benzoyl]-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine

Product 1

HCID 19600269N,N-dimethyl-[6-[4-(2-thenoyl)benzoyl]-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine hydrochloride

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

N,N-Dimethyl-[6-[4-(2-thenoyl)benzoyl]-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine 0.197 g was dissolved in 2 ml of methanol; hydrogen chloride in methanol was added in excess, followed by stirring. This mixture was then concentrated to yield the desired product.

Workup

  1. concentrationThis mixture was then concentrated

Sources & evidence

ORD record
ord-a030ab541076452aa35b6479edc17454
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

Loading…