Hydrochloric Acid → HCID 67586288, compound

HRID 611314Notes

Reaction equation

HRID 611314 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]\[C:10]2[CH:15]=[CH:14][C:13]([C:16]([N:18]3[CH2:23][CH2:22][C:21]4[CH:24]=[C:25]([CH2:27][N:28]5[CH2:32][CH2:31][CH2:30][CH2:29]5)[O:26][C:20]=4[CH2:19]3)=[O:17])=[CH:12][CH:11]=2)=[CH:4][CH:3]=1.Cl>CO>[ClH:1].[Cl:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]\[C:10]2[CH:11]=[CH:12][C:13]([C:16]([N:18]3[CH2:23][CH2:22][C:21]4[CH:24]=[C:25]([CH2:27][N:28]5[CH2:29][CH2:30][CH2:31][CH2:32]5)[O:26][C:20]=4[CH2:19]3)=[O:17])=[CH:14][CH:15]=2)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 67586166HCID 67586166, compound

Product 1

HCID 67586288HCID 67586288, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

(Z)-6-(4-Chlorostilbene-4'-carbonyl)-2-(1-pyrrolidinylmethyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridine 0.768 g was dissolved in 2 ml of methanol; hydrogen chloride in methanol was added in excess, followed by stirring. This mixture was concentrated to yield the desired product.

Workup

  1. concentrationThis mixture was concentrated

Sources & evidence

ORD record
ord-02ed7e5eb00f49d38100efb89f0e7e1d
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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