Hydrochloric Acid → HCID 19600219, compound

HRID 611383Notes

Reaction equation

HRID 611383 reaction equation
[C:1]1([C:7]2([C:10]3[CH:32]=[CH:31][C:13]([C:14]([N:16]4[CH2:21][CH2:20][C:19]5[CH:22]=[C:23]([CH2:25][N:26]6[CH2:30][CH2:29][CH2:28][CH2:27]6)[O:24][C:18]=5[CH2:17]4)=[O:15])=[CH:12][CH:11]=3)[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:33]>CO>[ClH:33].[C:1]1([C:7]2([C:10]3[CH:11]=[CH:12][C:13]([C:14]([N:16]4[CH2:21][CH2:20][C:19]5[CH:22]=[C:23]([CH2:25][N:26]6[CH2:30][CH2:29][CH2:28][CH2:27]6)[O:24][C:18]=5[CH2:17]4)=[O:15])=[CH:31][CH:32]=3)[CH2:8][CH2:9]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19599917HCID 19599917, compound

Product 1

HCID 19600219HCID 19600219, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

6-[4-(1-Phenylcyclopropyl)benzoyl]-2-(1-pyrrolidinylmethyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridine 0.481 g was dissolved in 2 ml of methanol; hydrogen chloride in methanol was added in excess, followed by stirring. This mixture was concentrated to yield the desired product.

Workup

  1. concentrationThis mixture was concentrated

Sources & evidence

ORD record
ord-6ffbb68dec994dc2ae95a2d7fceab7af
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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