Hydrochloric Acid → HCID 19600210, compound

HRID 611390Notes

Reaction equation

HRID 611390 reaction equation
[C:1]1([C:7]2([C:12]3[CH:34]=[CH:33][C:15]([C:16]([N:18]4[CH2:23][CH2:22][C:21]5[CH:24]=[C:25]([CH2:27][N:28]6[CH2:32][CH2:31][CH2:30][CH2:29]6)[O:26][C:20]=5[CH2:19]4)=[O:17])=[CH:14][CH:13]=3)[S:11][CH2:10][CH2:9][S:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:35]>CO>[ClH:35].[C:1]1([C:7]2([C:12]3[CH:34]=[CH:33][C:15]([C:16]([N:18]4[CH2:23][CH2:22][C:21]5[CH:24]=[C:25]([CH2:27][N:28]6[CH2:29][CH2:30][CH2:31][CH2:32]6)[O:26][C:20]=5[CH2:19]4)=[O:17])=[CH:14][CH:13]=3)[S:8][CH2:9][CH2:10][S:11]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19600199HCID 19600199, compound

Product 1

HCID 19600210HCID 19600210, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

6-[4-(2-Phenyl-1,3-dithiolan-2-yl)benzoyl]-2-(1-pyrrolidinylmethyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridine 0.624 g was dissolved in 2 ml of methanol; hydrogen chloride in methanol was added in excess, followed by stirring. This mixture was concentrated to yield the desired product.

Workup

  1. concentrationThis mixture was concentrated

Sources & evidence

ORD record
ord-3dba4f00c2d3430da45827af1ac70fff
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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