Hydrochloric Acid → HCID 19600227, compound

HRID 611401Notes

Reaction equation

HRID 611401 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:30][C:8]2[CH2:9][N:10]([S:13]([C:16]3[CH:21]=[CH:20][C:19]([C:22](=[O:29])[C:23]4[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=4)=[CH:18][CH:17]=3)(=[O:15])=[O:14])[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3].[ClH:31]>CO>[ClH:31].[CH3:3][N:2]([CH2:4][C:5]1[O:30][C:8]2[CH2:9][N:10]([S:13]([C:16]3[CH:21]=[CH:20][C:19]([C:22](=[O:29])[C:23]4[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=4)=[CH:18][CH:17]=3)(=[O:15])=[O:14])[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:1]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19600131HCID 19600131, compound

Product 1

HCID 19600227HCID 19600227, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

N,N-Dimethyl-[6-(4-benzoylphenylsulfonyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine 79 mg was dissolved in 2 ml of methanol; hydrogen chloride in methanol was added in excess, followed by stirring. This mixture was concentrated to yield the desired product.

Workup

  1. concentrationThis mixture was concentrated

Sources & evidence

ORD record
ord-5f54749ff2aa448d9ec56ea7d57d4301
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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