Hydrochloric Acid → HCID 19600078, compound

HRID 611416Notes

Reaction equation

HRID 611416 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([S:14]([C:17]3[CH:22]=[CH:21][C:20]([CH2:23][CH2:24][C:25]4[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=4)=[CH:19][CH:18]=3)(=[O:16])=[O:15])[CH2:8][C:7]=2[CH:6]=1)[CH3:3].[ClH:31]>CO>[ClH:31].[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([S:14]([C:17]3[CH:22]=[CH:21][C:20]([CH2:23][CH2:24][C:25]4[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=4)=[CH:19][CH:18]=3)(=[O:16])=[O:15])[CH2:8][C:7]=2[CH:6]=1)[CH3:3]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19600079HCID 19600079, compound

Product 1

HCID 19600078HCID 19600078, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

N,N-Dimethyl-[5-(4-phenethylbenzenesulfonyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine 0.171 g was dissolved in 2 ml of methanol; hydrogen chloride in methanol was added in excess, followed by stirring. This mixture was concentrated; the resulting solid was washed with diethyl ether to yield the desired product.

Workup

  1. concentrationThis mixture was concentrated
  2. washthe resulting solid was washed with diethyl ether

Sources & evidence

ORD record
ord-4d7fcf8fe6ad4f63a9adcc2177dbeb52
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

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