Hydrochloric Acid → HCID 67585394, compound

HRID 611422Notes

Reaction equation

HRID 611422 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4](/[CH:8]=[CH:9]\[C:10]2[CH:15]=[CH:14][C:13]([S:16]([N:19]3[CH2:24][CH2:23][C:22]4[O:25][C:26]([CH2:28][N:29]5[CH2:33][CH2:32][CH2:31][CH2:30]5)=[CH:27][C:21]=4[CH2:20]3)(=[O:18])=[O:17])=[CH:12][CH:11]=2)[CH:5]=[CH:6][CH:7]=1.Cl>CO>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4](/[CH:8]=[CH:9]\[C:10]2[CH:11]=[CH:12][C:13]([S:16]([N:19]3[CH2:24][CH2:23][C:22]4[O:25][C:26]([CH2:28][N:29]5[CH2:30][CH2:31][CH2:32][CH2:33]5)=[CH:27][C:21]=4[CH2:20]3)(=[O:17])=[O:18])=[CH:14][CH:15]=2)[CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 67584924HCID 67584924, compound

Product 1

HCID 67585394HCID 67585394, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

(Z)-5-(3-Chlorostilbene-4'-sulfonyl)-2-(1-pyrrolidinylmethyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridine 0.613 g was dissolved in 2 ml of methanol; hydrogen chloride in methanol was added in excess, followed by stirring. This mixture was concentrated; the resulting solid was washed with diethyl ether to yield the desired product.

Workup

  1. concentrationThis mixture was concentrated
  2. washthe resulting solid was washed with diethyl ether

Sources & evidence

ORD record
ord-d272a40d214340b0b2c3bb448cc7abc1
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

Loading…