Hydrochloric Acid → 5-benzyl-2-dimethylaminomethyl-6,7-dihydro-5H-furo[3,2-c]pyridin-4-one hydrochloride

HRID 611428Notes

Reaction equation

HRID 611428 reaction equation
[CH2:1]([N:8]1[CH2:13][CH2:12][C:11]2[O:14][C:15]([CH2:17][N:18]([CH3:20])[CH3:19])=[CH:16][C:10]=2[C:9]1=[O:21])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:22]>CO>[ClH:22].[CH2:1]([N:8]1[CH2:13][CH2:12][C:11]2[O:14][C:15]([CH2:17][N:18]([CH3:19])[CH3:20])=[CH:16][C:10]=2[C:9]1=[O:21])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 196001075-benzyl-2-dimethylaminomethyl-6,7-dihydro-5H-furo[3,2-c]pyridin-4-one

Product 1

HCID 196002095-benzyl-2-dimethylaminomethyl-6,7-dihydro-5H-furo[3,2-c]pyridin-4-one hydrochloride

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

5-Benzyl-2-dimethylaminomethyl-6,7-dihydro-5H-furo[3,2-c]pyridin-4-one 0.110 g was dissolved in 2 ml of methanol; hydrogen chloride in methanol was added in excess, followed by stirring. This mixture was concentrated; the resulting solid was washed with diethyl ether to yield the desired product.

Workup

  1. concentrationThis mixture was concentrated
  2. washthe resulting solid was washed with diethyl ether

Sources & evidence

ORD record
ord-33286c0495df4938919ef7c7165db0ba
Source dataset
uspto-grants-1999_12
Patent number
US05998433

Reaction notes

Loading…