HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 15342560, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium cyanate | HCID 11378442 | — |
| Reactant | HCID 15346298 | HCID 15346298 | — |
| Solvent | Sulfolane | HCID 31347 | — |
| Product | HCID 15342560 | HCID 15342560 | 57% |
Reaction Steps
Hydrogen chloride is passed into 1 g of methyl 4-chloro-N-(methoxycarbonylmethyl)anthranilate and 1.6 g of potassium cyanate in 20 ml of sulfolane at 50° C. until analysis by HPLC indicates complete conversion. The product is precipitated by addition of water, filtered off, washed with water and dried. 0.59 g (57%) of methyl 1,2,3,4-tetrahydro-7-chloro-2,4-dioxoquinazolin-1-ylacetate is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06001831 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-ea37c61992fb4c599b247a0301cafa8a |
| Source note | uspto-grants-1999_12 |