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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 61149Generated: October 26, 2026

5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid → HCID 117727855, compound

https://huagongshe.com/reaction/61149

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acidHCID 53260165—
Reactant2-((4,4-Difluoropiperidin-2-yl)methyl)isoindoline-1,3-dioneHCID 117728017—
Reactant((2S,3R)-2-(Aminomethyl)-3-methylpiperidin-1-yl)(5-methyl-2-(1-methyl-1H-pyrazol-4-yl)phenyl)methanoneHCID 117728145—
ProductHCID 117727855HCID 117727855—

Reaction Steps

The title compound was prepared following the same general protocol as described for ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(5-methyl-2-(1-methyl-1H-pyrazol-4-yl)phenyl)methanone in Example A1 using 5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoic acid and 2-((4,4-difluoropiperidin-2-yl)methyl)isoindoline-1,3-dione. MS (ESI) 336 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-50ccac2f3e294a3e9fbf061a167c3080
Source noteuspto-grants-2016_09