HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18329364, compound → HCID 53721492, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18329364 | HCID 18329364 | — |
| Reactant | HCID 53769083 | HCID 53769083 | — |
| Catalyst | Tetrakis(triphenylphosphine)palladium | HCID 11979704 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 53721492 | HCID 53721492 | — |
Reaction Steps
To a solution of 2-(1-methyl-2-(R)-pyrrolidinyl)-6-(bromo)-furo[3,2-b]pyridine from Example 47 in toluene are added (5-methyl3-pyridyl)tributyltin and tetrakis(triphenylphosphine)palladium(O). After being refluxed overnight, the resulting mixture is cooled to room temperature. Solvent is removed, and the residue is chromatographed on a silica gel column.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06001849 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-9cc387c3718443b8b8df5aa90fac5855 |
| Source note | uspto-grants-1999_12 |