反应详情

O-(2-hydroxy-3-piperidino-propyl)-hydroxylamine (1,85 g, 0,011 mol) was dissolved in 30 ml chloroform and 1,17 ml (0,011 mol) n-hexyl-isocyanate was added while stirring. After 3 hours the reaction mixture was evaporated and purified by column chromatography. The oil thus obtained crystallizes slowly in refrigerator and rubbing the crystals in petroleum ether a white material was obtained.

1. customAfter 3 hours the reaction mixture was evaporated
2. custompurified by column chromatography
3. customThe oil thus obtained
4. customcrystallizes slowly in refrigerator
5. customwas obtained