tert-Butyl isocyanate → HCID 19598345, compound

Participants

Reaction Steps

O-(2-hydroxy-3-diethylamino-propyl)-hydroxylamine was dissolved in 40 ml abs chloroform and 3,08 ml (0,027 mol) tert-butyl isocyanate was added thereto dropwise. The mixture was stirred at room temperature for 15 hours and evaporated. The product thus obtained was purified by column chromatography. The material thus obtained is in oily form which crystallizes when storing in refrigerator. The crystals were filtered after trituration with petroleum ether. Yield: 1,44 g (20%). Mp.: 58-61° C.

Provenance & Evidence