Sodium Hydroxide → 197973-92-5

HRID 611789Notes

Reaction equation

HRID 611789 reaction equation
[C:1]([CH:6]1[CH2:11][CH2:10][CH2:9][N:8]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:7]1=[O:18])([O:3]CC)=[O:2].[OH-].[Na+]>CO>[C:1]([CH:6]1[CH2:11][CH2:10][CH2:9][N:8]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:7]1=[O:18])([OH:3])=[O:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 19597335HCID 19597335, compound

Product 1

HCID 19597331197973-92-5

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The product from Step C (0.551 g, 2.56 mmol) was dissolved in methanol (3 mL) and 5% aqueous sodium hydroxide added (3 mL). After 11 h, methanol was removed in vacuo, and the residue partitioned between ethyl acetate and 10% aqueous HCl. The organic layer was washed with saturated brine, and dried over MgSO4. The title compound was obtained as a white solid.

Workup

  1. custommethanol was removed in vacuo
  2. customthe residue partitioned between ethyl acetate and 10% aqueous HCl
  3. washThe organic layer was washed with saturated brine
  4. dry with materialdried over MgSO4

Sources & evidence

ORD record
ord-d61641d03e614d8fb3cd49991fce9e85
Source dataset
uspto-grants-1999_12
Patent number
US06001835

Reaction notes

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