Phosgene → 2-Ethylhexanoyl chloride

HRID 611952Notes

Reaction equation

HRID 611952 reaction equation
[CH2:1]([CH:3]([CH2:7][CH2:8][CH2:9][CH3:10])[C:4](O)=[O:5])[CH3:2].C(Cl)([Cl:13])=O>ClC1C=CC=CC=1>[CH2:1]([CH:3]([CH2:7][CH2:8][CH2:9][CH3:10])[C:4]([Cl:13])=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 6371PhosgeneHCID 86972-Ethylhexanoic Acid

Product 1

HCID 791032-Ethylhexanoyl chloride

Reagents, catalysts & solvents 1

HCID 7964ChlorobenzeneSolvent

Conditions

Temperature
25 °C

Procedure

87 g (0.6 mol) of 2-ethylhexanoic acid and 890 g of monochlorobenzene are introduced into the reactor and 607 g (6.14 mol) of phosgene are then added over about 30 minutes, while maintaining the temperature of the reaction medium at a maximum of 25° C. The set pressure is adjusted to 10.5 bar relative and the reaction medium is heated. The reaction is complete after one hour 30 minutes. The levels of residual acid and anhydride are zero and the level of 2-ethylhexanoyl chloride obtained is greater than 99.8 mol %.

Workup

  1. additionare then added over about 30 minutes
  2. temperaturethe reaction medium is heated

Sources & evidence

ORD record
ord-bf5a825e23384e65a343c921d1cf4299
Source dataset
uspto-grants-1999_12
Patent number
US06002043

Reaction notes

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