HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoro-5-(trifluoromethyl)pyridine → HCID 117727852, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoro-5-(trifluoromethyl)pyridine | HCID 5463754 | — |
| Reactant | ((2S,3R)-2-(Aminomethyl)-3-methylpiperidin-1-yl)(2-fluoro-6-(pyrimidin-2-yl)phenyl)methanone | HCID 117727763 | — |
| Product | HCID 117727852 | HCID 117727852 | — |
Reaction Steps
The title compound was prepared following the same general protocol as described for Example A1 using ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(6-fluoro-2-(pyrimidin-2-yl)phenyl)methanone and 2-fluoro-5-(trifluoromethyl)pyridine. ESI-MS (m/z): 474 [M+1]+. 1H NMR (500 MHz, DMSO-d6) δ 8.90-6.50 (m, 10H), 4.95-2.70 (m, 5H), 2.00-0.65 (m, 8H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09440982B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-11c7c639433b42208b2e718a7943efd6 |
| Source note | uspto-grants-2016_09 |