HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-fluoroaniline → 4-(4-Chloro-2-fluorophenylamino)-7-methoxy-3-quinolinecarbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-fluoroaniline | HCID 93898 | — |
| Reactant | 4-Chloro-7-methoxyquinoline-3-carbonitrile | HCID 12559431 | — |
| Product | 4-(4-Chloro-2-fluorophenylamino)-7-methoxy-3-quinolinecarbonitrile | HCID 22466662 | — |
Reaction Steps
In the manner of Example 274 reaction of 4chloro-7-methoxy-3-quinolinecarbonitrile with 4-chloro-2-fluoroaniline gave the title compound as an amber solid, mp 208-210° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06002008 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-3ebc623e443e41b8b861a272e6753e54 |
| Source note | uspto-grants-1999_12 |