3,4-Dimethylaniline → HCID 19593892, compound

HRID 612318Notes

Reaction equation

C[C:2]1[CH:3]=[C:4]([CH:6]=[CH:7][C:8]=1[CH3:9])[NH2:5].[CH3:10][CH:11]1[CH2:16][CH2:15][CH2:14][CH2:13][C:12]1=O.N1C2C=CC=C[C:21]=2N=N1>>[CH3:10][CH:11]1[CH2:16][CH2:15][CH2:14][CH2:13][CH:12]1[NH:5][C:4]1[CH:3]=[CH:2][C:8]([CH3:9])=[CH:7][C:6]=1[CH3:21]

Participants

Reactant 3

HCID 72483,4-Dimethylaniline

HCID 114192-Methylcyclohexanone

HCID 178418385HCID 178418385, compound

Product 1

HCID 19593892HCID 19593892, compound

Conditions

Temperature: 120 °C

Procedure

In a 100-mL flask, the following mixture is heated at 120° C. for 24 h: 12 g 3,4-dimethylaniline, 11 g 2-methylcyclohexanone and 12 g benzotriazole. The 2-methylcyclohexyl-2,4-dimethylphenylamine is isolated after reduction, as in step 1 of Example 1. 18 g of an oily product are isolated.

Sources & evidence

ORD record: ord-332d337a133e4ded86b045c7aee1e363
Source dataset: uspto-grants-1999_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06004486

Reaction notes

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