HRID612338

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID67898

2-Bromo-1,1,1-trifluoroethane

C2H2BrF3

结构：CCCCC[Si]1(c2ccccc2)CCC(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)CC1.[I-]

HCID19593804

未命名化合物

结构：CC(C)(C)[Si](C)(C)Oc1ccc(-c2ccc(C=O)cc2)cc1F

HCID19593836

未命名化合物

PRODUCTS

生成物

结构：CCCCC[Si@H]1CC[C@H](CCc2ccc(-c3ccc(OCC(F)(F)F)c(F)c3)cc2)CC1

HCID178447746

未命名化合物

PROCEDURE

实验过程

The general procedure of Example 56 was repeated using (4-pentyl-4-phenyl-4-silacyclohexyl)methyltriphenylphosphonium iodide, 4'-formyl-3-fluoro-4-(t-butyldimethylsiloxy)biphenyl and 1-bromo-2, 2,2-trifluoroethane, thereby obtaining the intended compound.

WORKUP

后处理

customobtaining the intended compound

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d676946764974369a06beb395fdad7b3
来源数据集: uspto-grants-1999_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06004478
来源说明: uspto-grants-1999_12

反应 SMILES

[I-].C([Si:7]1([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35]C=2)[CH2:12][CH2:11][CH:10]([CH2:13][P+](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[CH2:9][CH2:8]1)CCCC.[CH:39]([C:41]1[CH:46]=[CH:45][C:44]([C:47]2[CH:52]=[CH:51][C:50]([O:53][Si](C(C)(C)C)(C)C)=[C:49]([F:61])[CH:48]=2)=[CH:43][CH:42]=1)=O.Br[CH2:63][C:64]([F:67])([F:66])[F:65]>>[CH2:33]([Si@H:7]1[CH2:8][CH2:9][C@H:10]([CH2:13][CH2:39][C:41]2[CH:42]=[CH:43][C:44]([C:47]3[CH:52]=[CH:51][C:50]([O:53][CH2:63][C:64]([F:67])([F:66])[F:65])=[C:49]([F:61])[CH:48]=3)=[CH:45][CH:46]=2)[CH2:11][CH2:12]1)[CH2:38][CH2:37][CH2:36][CH3:35]