Hydrochloric Acid → HCID 53805009, compound

Participants

Reaction Conditions

Reaction Steps

3-(2,4-Dichlorophenoxy)-4-methylsulphonylaminobenzene-sulphonic acid chloride (1.08 g, 2.50 mmol) was dissolved in dichloromethane (5 ml) and at 0° C. added dropwise to a solution of diethylamine (0.30 ml, 2.51 mmol) in pyridine (20 ml). The mixture was stirred for 1 hour at 0° C., acidified with 1N HCl and extracted with ethyl acetate. The combined organic phases were dried over MgSO4 and the solvent was evaporated off. The residue was purified by chromatography (silica gel, CH2Cl2). Yield: 0.22 g=19% 13C (100 MHz, DMSO-d6) δ 149.98, 147.50, 136.21, 132.37, 130.43, 129.63, 129.21, 126.15, 123.56, 122.86, 122.72, 114.90, 41.77, 41.02, 14.02

Provenance & Evidence