反应详情

A solution of 5-acetoxyphthalic anhydride (3.03 g), 4-hydrazinopyridine hydrochloride (2.04 g) and glacial acetic acid (15 ml) was heated under reflux, under nitrogen, for 4 hrs, with stirring. The reaction mixture was cooled to ambient temperature, the precipitate was collected, washed with water and dried at 60° C. under vacuum overnight. Trituration with hot absolute ethanol gave 2.3 g (56%) of product, mp >260° C.

1. temperatureunder reflux, under nitrogen, for 4 hrs
2. customthe precipitate was collected
3. washwashed with water
4. customdried at 60° C. under vacuum overnight