Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuric acid magnesium salt (1:1) → N-[3-(3-Methoxyphenyl)propylidene]-N'-(4-pyridinyl)hydrazine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuric acid magnesium salt (1:1) | HCID 24083 | — |
| 반응물 | 3-(3-Methoxyphenyl)propionaldehyde | HCID 11423769 | — |
| 반응물 | 4-Hydrazinylpyridine hydrochloride | HCID 22320258 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | N-[3-(3-Methoxyphenyl)propylidene]-N'-(4-pyridinyl)hydrazine hydrochloride | HCID 70107610 | 61% |
반응 단계
A slurry of 3-(3-methoxyphenyl)propionaldehyde (6.46 g), 4-hydrazinopyridine hydrochloride (6.30 g) and magnesium sulfate (5 g) in ethanol (75 ml) was heated under reflux, under nitrogen, with stirring, for 45 mins. The reaction mixture was filtered, the filter cake was washed with ethyl acetate, and the filtrate was concentrated in vacuo. The residue was triturated with ethyl acetate to give 7 g (61%) of product, mp 155-156° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06004977 |
| 출처 데이터셋 | uspto-grants-1999_12 |
| ORD ID | ord-94ca095354cf45b59cf18d606a9ab0bc |
| 출처 메모 | uspto-grants-1999_12 |