Ethyl formate → HCID 12228443, compound

HRID 612493Notes

Reaction equation

HRID 612493 reaction equation
[NH2:1][CH2:2][C:3]1[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=1.[CH:9](OCC)=[O:10]>>[N:6]1[CH:7]=[CH:8][C:3]([CH2:2][NH:1][CH:9]=[O:10])=[CH:4][CH:5]=1

Participants

3

Reactant 2

HCID 8025Ethyl formateHCID 773174-Pyridinemethanamine

Product 1

HCID 12228443HCID 12228443, compound

Procedure

A solution of 4-(aminomethyl)pyridine (54.1 g, 0.5 mol) and ethyl formate (44.4 ml) was refluxed for two hours and then permitted to stand at ambient temperature for 16 hours. The reaction was distilled to produce 61.6 g of N-(4-pyridylmethyl)formamide.

Workup

  1. distillationThe reaction was distilled

Sources & evidence

ORD record
ord-cbb18c223f0d48aea293ef798602487f
Source dataset
uspto-grants-1999_12
Patent number
US06004982

Reaction notes

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