Potassium Carbonate → HCID 19595476, compound

Participants

Reaction Steps

A mixture of 4-[2-(2,3-dimethoxyphenyl)-1-(trifluoro acetyloxy)ethyl]piperidine trifluoroacetamide compound (2.3 g, 6.0 mmol), K2CO3 (powdered, 1.0 g 6.6 mmol) and anhydrous methanol (15 ml) was stirred at ambient temperature for 3 h. The reaction was filtered and the filtrate concentrated to 2.3 g of a thick, yellow oil. The oil was triturated with Et2O (a white solid resulted). The solid was filtered, and the filtrate concentrated to afford a thick yellow oil.

Provenance & Evidence