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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 61254Generated: October 27, 2026

2-Fluoro-5-(trifluoromethyl)pyrimidine → HCID 117727934, compound

https://huagongshe.com/reaction/61254

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-(trifluoromethyl)pyrimidineHCID 20071885—
Reactant5-cyano-2-(2H-1,2,3-triazol-2-yl)benzoic acidHCID 67982592—
Reactant2-(((2S,3R)-3-Methylpiperidin-2-yl)methyl)isoindoline-1,3-dioneHCID 117727630—
ProductHCID 117727934HCID 117727934—

Reaction Steps

The title compound was prepared following the same general protocol as described in Example A1, using 5-cyano-2-(2H-1,2,3-triazol-2-yl)benzoic acid, 2-(((2S,3R)-3-methylpiperidin-2-yl)methyl)isoindoline-1,3-dione and 2-fluoro-5-(trifluoromethyl)pyrimidine. ESI-MS (m/z): 471 [M+1]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09440982B2
Source datasetuspto-grants-2016_09
ORD IDord-76309cdf7292464aa9da85d353630a3e
Source noteuspto-grants-2016_09