HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-(trifluoromethyl)pyrimidine → HCID 117727714, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-(trifluoromethyl)pyrimidine | HCID 13317019 | — |
| Reactant | 4-Methyl-2-(pyrimidin-2-yl)benzoic acid | HCID 68166618 | — |
| Reactant | 2-(((2S,3R)-3-Methylpiperidin-2-yl)methyl)isoindoline-1,3-dione | HCID 117727630 | — |
| Product | HCID 117727714 | HCID 117727714 | — |
Reaction Steps
The title compound was prepared following the same general protocol as described for Example A389 using 2-(((2S,3R)-3-methylpiperidin-2-yl)methyl)isoindoline-1,3-dione, 4-Methyl-2-(pyrimidin-2-yl)benzoic acid and 2-chloro-5-(trifluoromethyl)pyrimidine. 1H NMR (500 MHz, CD3OD) δ 9.00-6.70 (m, 8H), 5.15-2.85 (m, 5H), 2.45-0.65 (m, 11H); ESI MS (M+H) 471.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09440982B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-29de2b8b5fe54f48add890039b82f115 |
| Source note | uspto-grants-2016_09 |