Iodoethane → HCID 19596519, compound

HRID 612905Notes

Reaction equation

C(OC([NH:8][CH2:9][CH2:10][O:11][C:12]1[CH:16]=[C:15]([C:17]2[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][C:18]=2[Cl:24])[O:14][N:13]=1)=O)(C)(C)C.[CH2:25](I)[CH3:26]>>[ClH:23].[NH2:8][CH2:9][CH2:10][O:11][C:12]1[CH:16]=[C:15]([C:17]2[CH:22]=[CH:21][C:20]([Cl:23])=[C:19]([CH2:25][CH3:26])[C:18]=2[Cl:24])[O:14][N:13]=1

Participants

Reactant 2

HCID 6340Iodoethane

HCID 19596531HCID 19596531, compound

Product 1

HCID 19596519HCID 19596519, compoundYield 78%

Procedure

3-(2-(N-tert-Butoxycarbonylamino)ethoxy)-5-(2,4-dichlorophenyl)isoxazole (0.3 g) and ethyl iodide (0.1 ml) were subjected to reaction and post-treatment in a similar manner to that described in Example 14(a) to obtain the title compound (0.25 g, 78%) as a colorless powder.

Sources & evidence

ORD record: ord-19f329a22eb64db7b07934befc5e4526
Source dataset: uspto-grants-1999_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06005116

Reaction notes

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