Sodium Hydroxide → HCID 178438897, compound

HRID 612953Notes

Reaction equation

HRID 612953 reaction equation
C([O:3][C:4](=O)[C:5](Br)=[C:6](Br)[C:7]1[CH:12]=[CH:11][C:10]([CH:13]([CH3:15])[CH3:14])=[CH:9][CH:8]=1)C.Cl.[NH2:20][OH:21].[OH-].[Na+]>>[OH:3][C:4]1[CH:5]=[C:6]([C:7]2[CH:12]=[CH:11][C:10]([CH:13]([CH3:15])[CH3:14])=[CH:9][CH:8]=2)[O:21][N:20]=1

Participants

4

Reactant 3

HCID 14798Sodium HydroxideHCID 443297Hydroxyamine hydrochlorideHCID 54462131HCID 54462131, compound

Product 1

HCID 178438897HCID 178438897, compoundYield 71%

Procedure

α,β-Dibromo-4-isopropylcinnamic acid ethyl ester (9.5 g), hydroxylamine hydrochloride (2.2 g) and sodium hydroxide (5.2 g) were subjected to reaction and post-treatment in a similar manner to that described in Reference example 10(c) to obtain the title compound (3.6 g, 71%) as colorless crystals.

Sources & evidence

ORD record
ord-1174af20fabc407d879dfbb7040ff082
Source dataset
uspto-grants-1999_12
Patent number
US06005116

Reaction notes

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