Sodium Hydroxide → HCID 178515643, compound

HRID 612956Notes

Reaction equation

HRID 612956 reaction equation
C([O:3][C:4](=O)[C:5](Br)=[C:6](Br)[C:7]1[CH:12]=[CH:11][C:10]([O:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:9][CH:8]=1)C.Cl.[NH2:24][OH:25].[OH-].[Na+]>>[OH:3][C:4]1[CH:5]=[C:6]([C:7]2[CH:12]=[CH:11][C:10]([O:13][C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[CH:9][CH:8]=2)[O:25][N:24]=1

Participants

4

Reactant 3

HCID 14798Sodium HydroxideHCID 443297Hydroxyamine hydrochlorideHCID 53760946HCID 53760946, compound

Product 1

HCID 178515643HCID 178515643, compoundYield 83%

Procedure

α,β-Dibromo-4-phenoxycinnamic acid ethyl ester (7.0 g), hydroxylamine hydrochloride (1.4 g) and sodium hydroxide (3.3 g) were subjected to reaction and post-treatment in a similar manner to that described in Reference example 10(c) to obtain the title compound (3.4 g, 83%) as colorless crystals.

Sources & evidence

ORD record
ord-8c2aecae65824528812871471c0fd298
Source dataset
uspto-grants-1999_12
Patent number
US06005116

Reaction notes

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