HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 5-Amino-4-(2-chlorobenzoyl)-3-methyl-1-(2,4,6-trichlorophenyl)pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | 5-(2-Chlorobenzamido)-4-(2-chlorobenzoyl)-3-methyl-1-(2,4,6-trichlorophenyl)pyrazole | HCID 18427792 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 5-Amino-4-(2-chlorobenzoyl)-3-methyl-1-(2,4,6-trichlorophenyl)pyrazole | HCID 12972141 | — |
Reaction Steps
A solution of 1.94 g (3.50 mmol of the product of Step B in 20 mL of glacial acetic acid was treated with 20 mL of 48% hydrogen bromide and stirred at reflux for 8 hours. The cooled reaction mixture was treated with water to crystallize the product which was separated by filtration, washed with water and air dried to give the title product, 1.45 g (100%), m.p. softens about 210° C. and melts at 220° C. Anal. Calcd. for C17H11ON3Cl4 : 412.9656. Found: 412.9722.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06005109 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-c1703e5907ef48d18220c5e23fe61648 |
| Source note | uspto-grants-1999_12 |