Hydrochloric Acid → HCID 178443475, compound

HRID 613429Notes

Reaction equation

HRID 613429 reaction equation
[CH3:1][C:2]([CH3:16])([CH3:15])[CH2:3][CH2:4][C:5]#[C:6][C@@H:7]1[CH2:9][C@H:8]1[C:10]1[N:11]=[CH:12][NH:13][CH:14]=1.Cl>>[CH3:1][C:2]([CH3:16])([CH3:15])[CH2:3][CH2:4]/[CH:5]=[CH:6]\[C@H:7]1[CH2:9][C@H:8]1[C:10]1[N:11]=[CH:12][NH:13][CH:14]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 178443476HCID 178443476, compound

Product 1

HCID 178443475HCID 178443475, compound

Procedure

(1R,2R)-4-(2-(5,5-Dimethyl-cis-hex-1-enyl)cyclopropyl)imidazole was prepared by the Lindlar reduction of the compound 39 when it is trityl protected. The trityl group then deprotected after the Lindlar reduction by treating it with HCl at 90° C. for 1 h.

Sources & evidence

ORD record
ord-7268b9e9cd1c4fe7ac865ce83c7737ea
Source dataset
uspto-grants-1999_12
Patent number
US06008240

Reaction notes

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