HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 6-benzyloxy-2,2-dimethyl-2H-chromen
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | 6-Benzyloxy-2,2-dimethylchroman-4-ol | HCID 10869827 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 6-benzyloxy-2,2-dimethyl-2H-chromen | HCID 10901546 | 84.4% |
Reaction Steps
A solution of 9.6 g (33.8 mmol) of 6-benzyloxy-2,2-dimethylchroman-4-ol and 0.2 g of p-toluenesulfonic acid in 85 ml of toluene was heated under reflux on a water separator for 1 h. After cooling, the mixture was washed twice with sodium bicarbonate solution, dried over magnesium sulfate and concentrated i. vac., giving 7.6 g of 6-benzyloxy-2,2-dimethyl-2H-chromen.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06008245 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-9a35112c0a6d4d98abb3bbe4701f6622 |
| Source note | uspto-grants-1999_12 |