反应详情

A solution of 9.6 g (33.8 mmol) of 6-benzyloxy-2,2-dimethylchroman-4-ol and 0.2 g of p-toluenesulfonic acid in 85 ml of toluene was heated under reflux on a water separator for 1 h. After cooling, the mixture was washed twice with sodium bicarbonate solution, dried over magnesium sulfate and concentrated i. vac., giving 7.6 g of 6-benzyloxy-2,2-dimethyl-2H-chromen.

1. temperatureAfter cooling
2. washthe mixture was washed twice with sodium bicarbonate solution
3. dry with materialdried over magnesium sulfate
4. concentrationconcentrated i