1-Iodopropane → HCID 9862111, compound

HRID 613445Notes

Reaction equation

[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[O:8][C:7]([CH3:13])([CH3:12])[CH:6]=[C:5]2[N:14]([CH3:19])[S:15]([CH3:18])(=[O:17])=[O:16].I[CH2:21][CH2:22][CH3:23]>>[CH2:21]([O:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[O:8][C:7]([CH3:13])([CH3:12])[CH:6]=[C:5]2[N:14]([CH3:19])[S:15]([CH3:18])(=[O:17])=[O:16])[CH2:22][CH3:23]

Participants

Reactant 2

HCID 336431-Iodopropane

HCID 19593328HCID 19593328, compound

Product 1

HCID 9862111HCID 9862111, compound

Procedure

Similar to Example 8b, 0.5 g of N-(6-hydroxy-2,2-dimethyl-2H-chromen-4-yl)-N-methyl-methanesulfonamide was alkylated with 1 -iodopropane, giving 0.36 g of N-(6-propoxy-2,2-dimethyl-2H-chromen-4-yl)-N-methyl-methanesulfonamide; m.p. 93-95° C.

Sources & evidence

ORD record: ord-28ec3a1b0a594c94b0e2d509877a3da5
Source dataset: uspto-grants-1999_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06008245

Reaction notes

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