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HRID613472

反应详情

EQUATION

反应方程式

HRID 613472 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)NN
HCID70091

Hydrazinecarboxylic acid, 1,1-dimethylethyl ester

C5H12N2O2

结构：CCOC(=O)c1cnc2c([N+](=O)[O-])cccc2c1Cl
HCID11196760

ETHYL 4-CHLORO-8-NITROQUINOLINE-3-CARBOXYLATE

C12H9ClN2O4

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)n1[nH]c2c(cnc3c([N+](=O)[O-])cccc32)c1=O
HCID19593009

未命名化合物

收率 77.8%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1COCCO1
溶剂HCID31275

1,4-Dioxane

C4H8O2

PROCEDURE

实验过程

A mixture of 4-chloro-3-ethoxycarbonyl-8-nitroquinoline (500 mg) and tert-butoxycarbonylhydrazine (283 mg) in dioxane was refluxed for 1 hour. The mixture was concentrated in vacuo to give 2-tert-butoxycarbonyl-2,3-dihydro-6-nitro-1H-pyrazolo[4,3-c]quinolin-3-one (458 mg).

WORKUP

后处理

  1. temperaturewas refluxed for 1 hour
  2. concentrationThe mixture was concentrated in vacuo