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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 613503Generated: October 29, 2026

Sodium Hydroxide → HCID 19592865, compound

https://huagongshe.com/reaction/613503

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 19592651HCID 19592651—
SolventEthanolHCID 702—
SolventWaterHCID 962—
ProductHCID 19592865HCID 1959286594.7%

Reaction Steps

A mixture of 8-(2,6-dichlorobenzoylamino)-4-ethoxycarbonylmethylquinazoline (90 mg) and 1N sodium hydroxide solution (1 ml) in ethanol (5 ml) was refluxed for 30 minutes. The mixture was diluted with water, and the resulting precipitate was collected by filtration and washed with water to give 8-(2,6-dichlorobenzoylamino)-4-methylquinazoline (70 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06008230
Source datasetuspto-grants-1999_12
ORD IDord-d6311e6619ea46f9b9dfb337b323426a
Source noteuspto-grants-1999_12