Sodium Thiosulfate → HCID 19592642, compound

Participants

Reaction Steps

A solution of 8-(2,6-dichlorobenzoylamino)quinoline (100 mg) and m-chloroperbenzoic acid (71 mg) in ethylene chloride was stirred for 1 hour at 40° C. To the mixture was added 5% sodium thiosulfate solution, and the mixture was partitioned between dichloromethane and saturated sodium bicarbonate solution. The organic layer was dried over magnesium sulfate and evaporated in vacuo. The residue was recrystallized from dichloromethane-methanol to give 8-(2,6-dichlorobenzoylamino)quinoline 1-oxide (48 mg).

Provenance & Evidence